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This finding positions these omega-3 PUFAs as a promising treatment option, offering an effective alternative to the currently available pharmacological strategies which typically show limited efficacy and patient acceptability

Subchondral bone is an essential component of the joint, and the subchondral bone remodeling dominated by osteoclasts and osteoblasts can reflect the OA process [91, 92]

696 Fer-1 can also reduce the accumulation of iron and ROS, downregulate the ferroptosis-related genes PTGS2 and their products, thereby inhibiting the ferroptosis of oligodendrocytes, and finally alleviating the white matter injury after SCI in rats and promoting functional recovery

Chin Med J Pulm Crit Care Med